A nexus is a connection or the centre of something.
Nexus may refer to:

In computers and Internet

Nexus (Mortal Kombat), a central hub between the realms of existence in Mortal Kombat
Nexus: The Jupiter Incident, a strategy game by Mithis Entertainment
Nexus: The Kingdom of the Winds, a MMORPG by Kru Interactive
Armored Core: Nexus, the eighth title in the Armored Core series
Nexus, the shadow organisation in Warzone 2100
The Nexus, the central world in Primal
The Nexus, the Protoss central building in Starcraft
Nexus, the heart and brain of the t'lan warriors in Breakdown
Nexus, a famous dagger user in the game GunZ
The Nexus Age, a hub world in Uru: Ages Beyond Myst
Nexus Crystal, an item in World of Warcraft
The "Overwatch Nexus" in Half-Life 2
The Strogg Nexus in Quake 4
The NEXUS Missiles in Unreal Tournament 2004 In games

Nexus (magazine), an international bi-monthly alternative news magazine
Nexus Books, a pornography publishing company
Nexus Editrice, an Italian company publishing games, books and magazines
Daily Nexus, the University of California, Santa Barbara student newspaper
Nexus News, an Institute of Physics publication for physics students
The Nexus (journal), a journal edited by Kerry Bolton
The Nexus, an NSPA award-winning high-school student newspaper in Poway Unified School District, San Diego, CA In music

NEXUS International Broadcasting Association, a non-profit association of broadcasters and producers
Nexus Trafikk, a Norwegian bus company
Nexus, the Tyne and Wear Passenger Transport Executive's trading name
Nexus Productions, a film and animation company based in London
Nexus Learning, a non-profit learning community based in Princeton, New Jersey/Richmond, Virginia
Nexusis a national, nonprofit organization that designs and operates a wide range of treatment programs for children and adolescents who exhibit severe emotional and behavioral problems. In fiction

NEXUS (rocket), a heavy-lift booster concept designed by General Dymanics
NEXUS (frequent traveller program), border clearance program between the United States and Canada
Nexus Grammar System, a system of analysing text
Shimano nexus, a bicycle line
Family nexus, a common viewpoint of family members in psychiatry and psychology
2C-B or Nexus, a psychedelic entheogen drug
Nexus, a provision of the Constitution of Australia
Nexus, in sales and use tax, a minimum level of presence to be required for taxes